Manuscript in press NeuroImage An adaptive reflexive processing model of neurocognitive function: Supporting evidence from a large scale (n=100) fMRI study of an auditory oddball task
نویسندگان
چکیده
Kent A. Kiehl, Michael C. Stevens, Kristin R. Laurens, Godfrey Pearlson, Vince D. Calhoun, & Peter F. Liddle Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT Department of Psychiatry, Yale University School of Medicine, New Haven, CT, Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada, Department of Forensic Mental Health Science, Institute of Psychiatry, King’s College London,
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An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task.
Recent hemodynamic imaging studies have shown that processing of low probability task-relevant target stimuli (i.e., oddballs) and low probability task-irrelevant novel stimuli elicit widespread activity in diverse, spatially distributed cortical and subcortical systems. The nature of this distributed response supports the model that processing of salient and novel stimuli engages many brain re...
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Event-related potential (ERP) studies have shown that the neural systems engaged during performance of oddball tasks are sensitive to contextual manipulations, such as the number of stimulus classes. Some ERP components (i.e., N1) are modulated by the number of stimulus types, while others (i.e., P3) are not greatly affected. However, little is known about how these contextual manipulations aff...
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The auditory oddball task is a well-studied stimulus paradigm used to investigate the neural correlates of simple target detection. It elicits several classic event-related potentials (ERPs), the most prominent being the P300 which is seen as a neural correlate of subjects' detection of rare (target) stimuli. Though trial-averaging is typically used to identify and characterize such ERPs, their...
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